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There are no adequate and well-controlled studies in pregnant women. There are reports of ophthalmic abnormalities occurring in infants born to women on antituberculous therapy that included Myambutol. Myambutol should be used during pregnancy only if the benefit justifies the potential risk to the fetus.
If corrective glasses are order myambutol use prior to treatment.these must be worn during visual acuity testing. During 1 to 2 years of therapy.a refractive error may develop which must be corrected in order to obtain accurate test results. Testing the visual acuity through a pinhole eliminates refractive error. Patients developing visual abnormality during Myambutol treatment may show subjective visual symptoms before.or simultaneously with.the demonstration of decreases in visual acuity.and all patients receiving Myambutol should be questioned periodically about blurred vision and other subjective eye symptoms.
Subjects with CF will be given the antimycobacterial drugs in the fasting state.without supplemental pancreatic enzymes.
To help clear up your tuberculosis (TB) infection completely.you must keep taking this medicine for the full time of treatment.even if you begin to feel better. This is very important. It is also important that you do not miss any doses.
A. Myambutol (ethambutol) may produce decreases in visual acuity.which appear to be due to optic neuritis. This effect may be related to dose and duration of treatment and is generally reversible when administration of the drug is discontinued. However.irreversible blindness has been reported. Because this drug may have adverse effects on vision.physical examination should include ophthalmoscopy.finger perimetry and testing of color discrimination. In patients with visual defects such as cataracts.recurrent inflammatory conditions of the eye.optic neuritis.and diabetic retinopathy.the evaluation of changes in visual acuity is more difficult.and care should be taken to be sure the variations in order myambutol use are not due to the underlying disease conditions. In such patients.consideration order myambutol use be given to the relationship between benefits expected and possible visual deterioration since evaluation of visual order myambutol use is difficult. Optic neuropathy including optic neuritis or retrobulbar neuritis occurring in association with ethambutol therapy may be characterized by one or more of the following events. decreased visual acuity.scotoma.color blindness.and/or visual defect. These events have also been reported in the absence of a diagnosis of optic or retrobulbar neuritis. Patients should be advised to report promptly to their physician any change of visual acuity. The change in visual acuity may be unilateral or bilateral and hence each eye must be tested separately and both eyes tested together. Testing of visual acuity should be performed before beginning Myambutol therapy and periodically during drug administration.except that it should be done monthly when a patient is on a dosage of more than 15 mg per kilogram per day. Snellen eye charts are recommended for testing of visual acuity. Studies have shown that there are definite fluctuations of one or two lines of the Snellen chart in the visual acuity of many tuberculous patients not receiving Myambutol. If careful evaluation confirms the magnitude of visual change and fails to reveal another cause.Myambutol should be discontinued and the patient reevaluated at frequent intervals. Progressive decreases in visual acuity during therapy must be considered to be due to Myambutol. If corrective glasses are used prior to treatment.these must be worn during visual acuity testing. During 1 to 2 years of therapy.a refractive error may develop which must be corrected in order to obtain accurate test results. Testing the visual acuity through a pinhole eliminates refractive error. Patients developing visual abnormality during Myambutol treatment may show subjective visual symptoms before.or simultaneously with.the demonstration of decreases in visual acuity.and all patients receiving Myambutol order myambutol use be questioned periodically about blurred vision and other subjective eye symptoms. Recovery of visual acuity generally occurs over a period of weeks to months after the drug has been discontinued. Some patients have received MYAMBUTOL (ethambutol hydrochloride) again after such recovery without recurrence order myambutol use loss of visual acuity. Myambutol is contraindicated in patients who are unable to appreciate and report visual side effects or changes in vision (eg.young children.unconscious patients). Shereen A. Gharbia.PharmD T.
Before taking ethambutol.tell your doctor or pharmacist if you are allergic to it. or if you have any other allergies. This product may contain inactive ingredients.which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
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