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No clinical data availableDue to the metabolic pathway of raltegravir no interaction is expected.

Coadministration with drugsegCYP inducerswhere significant decreases in nevirapine plasma concentrations may occurwhich may result in loss of virologic response and possible resistance and cross-resistance to other NNRTIs.

Howeverpatients should be advised that they may experience adverse reactions such as fatigue during treatment with ViramuneThereforecaution should be recommended when driving a car or operating machineryIf patients experience fatigue they should avoid potentially hazardous tasks such as driving or operating machinery.

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sustiva is prescribed in the united states about twice as often as viramune.